Telangana Govt Hospital doctors perform liver transplantation in patients with Marfan and rare syndrome

Doctors at Ottomania General Hospital are from multiple specialties and perform liver transplants in patients with Marfan syndrome and hepatopulmonary syndrome (HPS). This image is for representation only. |Photo source: Nagara Gopal

In a medical breakthrough, doctors at the Ottomania General Hospital (OGH) run by the Telangana government in Hyderabad successfully performed liver transplants in patients with Marfan syndrome and very severe hepatopulmonary syndrome (HPS).

Breathing is damaged

The 37-year-old was diagnosed with Marfan’s syndrome as an adult. By then, he had reached the critical stage of HP. His breathing becomes severely damaged due to low oxygen levels caused by advanced liver disease.

What are HPS and Marfan syndrome?

Hepatopulmonary syndrome (HPS) is a rare and serious disease that causes low oxygen levels and enlargement of blood vessels in the lungs, making it difficult to breathe. Liver transplants are usually the only treatment. But in this case, the patient also has Marfan syndrome, a genetic disease that makes the body tissues fragile and increases the risk of heart problems. These factors make the surgery even more risky, said Ch Madhusudhan, a senior surgical gastroenterologist involved in the case.

A team of hepatologists, pulmonologists, cardiologists and transplant surgeons at the hospital spent months evaluating the patient’s condition. After extensive discussion and review of the global medical literature, the team concluded that despite the complex risks involved, liver transplantation remains the only viable treatment option.

“Despite challenges such as vascular fragility encountered during the operation, no significant complications were performed. In the days after the surgery, the patient’s oxygen levels began to stabilize and a significant improvement in respiratory function was observed. The ongoing follow-up showed promising recovery and enhanced quality of life,” said Dr. Madhusudhan.

“This is a milestone not only for our hospitals, but for the global medical community. Successfully managing such a rare and high-risk case demonstrates the ability to collaborate and innovate in modern medicine,” the surgeon said.